PATCH CONTAINING ISOSORBIDE DINITRATE AND PREPARED BY USING ADHESIVE MIXTURE

A patch containing isosorbide dinitrate, which can reduce the occurence of a rash and is excellent in percutaneous absorbability and tack strength. It is produced by forming a tacky layer comprising a tacky composition containing a pressure-sensitive adhesive and isosorbide dinitrate on a flexible s...

Full description

Saved in:
Bibliographic Details
Main Authors FUJII, TAKAO, IWATA, MAKOTO, FURUYA, MINORU, OHE, MICHISUKE
Format Patent
LanguageEnglish
French
Japanese
Published 31.08.1995
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:A patch containing isosorbide dinitrate, which can reduce the occurence of a rash and is excellent in percutaneous absorbability and tack strength. It is produced by forming a tacky layer comprising a tacky composition containing a pressure-sensitive adhesive and isosorbide dinitrate on a flexible support. The pressure-sensitive adhesive is a mixture of a silicone adhesive (A) and a polyvinyl acetate adhesive (B) in a weight ratio (A/B) of from 85/15 to 15/85. The weight ratio of the mixture (A+B) to the dinitrate ranges from 90/10 to 60/40. Timbre renfermant du dinitrate d'isosorbide, pouvant diminuer l'apparition d'une éruption cutanée, et présentant une absorbabilité percutanée et un pouvoir adhésif excellents. On produit ce timbre en formant sur un support souple une couche adhésive comportant une composition adhésive renfermant une colle de contact et du dinitrate d'isosorbide. La colle de contact est un mélange d'une colle au silicone (A) et d'une colle polyvinylique (B) selon un rapport pondéral (A/B) allant de 85/15 à 15/85. Le rapport pondéral entre le mélange (A+B) et le dinitrate est compris entre 90/10 et 60/40.
Bibliography:Application Number: WO1995JP00318