SUBSTITUTED AZETIDINONE AMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS

Azetidinone compounds pharmaceutically useful as inhibitors of tumour necrosis factor (TNF) production are disclosed of general formula (I) wherein Y is H, (1-4C)alkyl or (a) and X is thio, sulphinyl or sulphonyl. Composés d'azétidinone d'utilité pharmaceutique en tant qu'inhibiteurs...

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Bibliographic Details
Main Author CRAWLEY, GRAHAM, CHARLES
Format Patent
LanguageEnglish
French
Published 26.01.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Azetidinone compounds pharmaceutically useful as inhibitors of tumour necrosis factor (TNF) production are disclosed of general formula (I) wherein Y is H, (1-4C)alkyl or (a) and X is thio, sulphinyl or sulphonyl. Composés d'azétidinone d'utilité pharmaceutique en tant qu'inhibiteurs de la production du facteur de necrose tumorale (TNF), de la formule générale (I), dans laquelle Y représente H, alkyle (1-4C) ou (a), et X représente thio, sulfinyle ou sulfonyle.
Bibliography:Application Number: WO1994GB01466