DETERMINATION OF OLIGONUCLEOTIDES FOR THERAPEUTICS, DIAGNOSTICS AND RESEARCH REAGENTS

Oligonucleotides which selectively bind to target biomolecules may be determined by in vitro assay of a pool of random oligonucleotides for activity against said biomolecules, followed by recovery and characterization of selected oligonucleotides. Oligonucleotides so determined may be utilized for t...

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Bibliographic Details
Main Author BRUICE, THOMAS, W
Format Patent
LanguageEnglish
Published 18.03.1993
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:Oligonucleotides which selectively bind to target biomolecules may be determined by in vitro assay of a pool of random oligonucleotides for activity against said biomolecules, followed by recovery and characterization of selected oligonucleotides. Oligonucleotides so determined may be utilized for therapeutic, diagnostic and research reagent purposes. Des oligonucléotides qui se lient sélectivement à des biomolécules cibles peuvent être déterminés par dosage in vitro d'un groupe d'oligonucléotides pris au hasard, sur la base de leur activité contre lesdites biomolécules. Les oligonucléotides sélectionnés sont ensuite récupérés et identifiés. Les oligonucléotides ainsi déterminés peuvent être utilisés pour la production de réactifs thérapeutiques, diagnostiques et de recherche.
Bibliography:Application Number: WO1992US07489