STABLE FORMULATION OF VIRAL NEURAMINIDASE

Aqueous formulations of viruses having neuraminidase activity, such as influenza and parainfluenza viruses, are made thermostable by incorporating a sugar stabilizer, a pH 4-7 buffer, calcium ion, and optionally a nonionic detergent into the formulation. Formulations aqueuses de virus à activité de...

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Bibliographic Details
Main Authors MAHER, JAMES, F, CLINKSCALES, C., WORTH
Format Patent
LanguageEnglish
Published 11.07.1991
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Aqueous formulations of viruses having neuraminidase activity, such as influenza and parainfluenza viruses, are made thermostable by incorporating a sugar stabilizer, a pH 4-7 buffer, calcium ion, and optionally a nonionic detergent into the formulation. Formulations aqueuses de virus à activité de neuraminidase, par exemple virus grippaux et para-grippaux. Elles sont rendues thermostables par l'adjonction d'un stabilisant du sucre, d'un tampon de pH 4-7, d'un ion calcium, et éventuellement, d'un détergent non ionique.
Bibliography:Application Number: WO1990US07680