NOVEL PHYSIOLOGICALLY ACTIVE PROTEINACEOUS SUBSTANCE

• Main Authors: FUJIWARA, KAZUMI, OKABE, TETSURO, OGATA, TOMOKO, FUJIYOSHI, NOBUO, SATO, SEIJI
• Format: Patent
• Language: English; Japanese
• Published: 11.10.1984
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

A novel physiologically active proteinaceous substance having a DNA synthesis-accelerating effect, and a process for preparing this substance by culturing human myelogenous leukemia cell strain. Prospective applications of this substance include an immunoactivating agent, anemia-treating agent, wound-treating agent, and an additive to a serum-free medium for macrophage cells, fibroblasts, lymphoblasts, etc. as their growth factor. Nouvelle substance protéique physiologiquement active possédant un effet d'accélération de la synthèse de l'ADN, et procédé de préparation de cette substance par culture de souche cellulaire leucémique miélogène humaine. Des applications envisagées de cette substance comprennent un agent activateur de l'immunité, un agent de traitement de l'anémie, un agent de traitement des blessures et un additif pour un milieu exempt de sérum pour des cellules macrophages, des fibroblastes, des lymphoblastes, etc. en tant que leur facteur de croissance.