COMPOSITIONS AND METHODS TO MODULATE TUMOR MICROENVIRONMENT ASSOCIATED LONG NONCODING RNAS

Disclosed herein are modulators of a long non-coding RNA (IncRNA), wherein an expression of the IncRNA is associated with an activation of a cancer-associated fibroblast (CAP). Further provided herein are methods of inhibiting a growth of a solid tumor or facilitating access to a solid tumor in a su...

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Bibliographic Details
Main Authors BLESSING, Daniel, OUNZAIN, Samir, MOLLER TORDENMALM, Emely
Format Patent
LanguageEnglish
French
Published 26.12.2024
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Summary:Disclosed herein are modulators of a long non-coding RNA (IncRNA), wherein an expression of the IncRNA is associated with an activation of a cancer-associated fibroblast (CAP). Further provided herein are methods of inhibiting a growth of a solid tumor or facilitating access to a solid tumor in a subject in need thereof. La divulgation concerne des modulateurs d'un long ARN non codant (ARNInc), une expression de l'ARNInc étant associée à l'activation d'un fibroblaste associé au cancer (CAP). La divulgation concerne en outre des méthodes d'inhibition de la croissance d'une tumeur solide ou de facilitation de l'accès à une tumeur solide chez un sujet en ayant besoin.
Bibliography:Application Number: WO2024IB00333