ADVANCED RNA TARGETING (ARNATAR) FOR ANGIOTENSINOGEN

Disclosed herein are Advanced RNA Targeting (ARNATAR) dsRNA compounds targeting angiotensinogen (AGT), Such compounds are useful in methods for reducing expression of A GT and for therapeutically treating RAAS associated diseases, disorders and/or conditions, or symptoms thereof in a subject. Sont d...

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Bibliographic Details
Main Authors LIEU, Yen, ZHANG, Lingdi, WANG, Yanfeng, LIANG, Xuehai
Format Patent
LanguageEnglish
French
Published 19.12.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Disclosed herein are Advanced RNA Targeting (ARNATAR) dsRNA compounds targeting angiotensinogen (AGT), Such compounds are useful in methods for reducing expression of A GT and for therapeutically treating RAAS associated diseases, disorders and/or conditions, or symptoms thereof in a subject. Sont divulgués des composés d'ARNdb ciblant l'ARN avancé (ARNATAR) ciblant l'angiotensinogène (AGT). De tels composés sont utiles dans des méthodes de réduction de l'expression d'AGT et de traitement thérapeutique de maladies, de troubles et/ou d'états pathologiques associés à la RAAS, ou de symptômes de ceux-ci chez un sujet.
Bibliography:Application Number: WO2024US33852