PURIFICATION OF CAPSULAR POLYSACCHARIDES

Described herein are methods of purifying various S. pneumoniae serotype capsular polysaccharides from cell lysates, which improve the yield of polysaccharides while minimizing the amount of Host Cell Protein (HCP) in the product. L'invention concerne des procédés de purification de divers poly...

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Bibliographic Details
Main Authors DAVEY, Peter T, WONG, Marc, FENNELL, Brian, MA, Kathleen
Format Patent
LanguageEnglish
French
Published 10.10.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC MACROMOLECULAR COMPOUNDS
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
POLYSACCHARIDES
SEPARATION
SPIRITS
THEIR PREPARATION OR CHEMICAL WORKING-UP
TRANSPORTING
VINEGAR
WINE
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Summary:Described herein are methods of purifying various S. pneumoniae serotype capsular polysaccharides from cell lysates, which improve the yield of polysaccharides while minimizing the amount of Host Cell Protein (HCP) in the product. L'invention concerne des procédés de purification de divers polysaccharides capsulaires de sérotype S.pneumoniae à partir de lysats cellulaires, qui améliorent le rendement de polysaccharides tout en réduisant au minimum la quantité de protéine de cellule hôte (HCP) dans le produit.
Bibliography:Application Number: WO2024US22744