ROR1-TARGETING ANTIBODY, ANTIBODY-DRUG CONJUGATE COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF
Provided are a ROR1-targeting antibody, an antibody-drug conjugate comprising same, a preparation method therefor, and a use thereof. The ROR1-targeting antibody or an antigen-binding fragment thereof has a heavy chain variable region, a light chain variable region, and a complementarity determining...
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Format | Patent |
Language | Chinese English French |
Published |
26.09.2024
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Abstract | Provided are a ROR1-targeting antibody, an antibody-drug conjugate comprising same, a preparation method therefor, and a use thereof. The ROR1-targeting antibody or an antigen-binding fragment thereof has a heavy chain variable region, a light chain variable region, and a complementarity determining region (CDR). Additionally provided are an antibody-drug conjugate comprising the ROR1-targeting antibody or an antigen-binding fragment thereof, a preparation method therefor, and a use thereof.
L'invention concerne un anticorps ciblant ROR1, un conjugué anticorps-médicament le comprenant, un procédé de préparation correspondant et une utilisation associée. L'anticorps ciblant ROR1 ou un fragment de liaison à l'antigène de celui-ci a une région variable de chaîne lourde, une région variable de chaîne légère et une région déterminant la complémentarité (CDR). L'invention concerne en outre un conjugué anticorps-médicament comprenant l'anticorps ciblant ROR1 ou un fragment de liaison à l'antigène de celui-ci, son pr |
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AbstractList | Provided are a ROR1-targeting antibody, an antibody-drug conjugate comprising same, a preparation method therefor, and a use thereof. The ROR1-targeting antibody or an antigen-binding fragment thereof has a heavy chain variable region, a light chain variable region, and a complementarity determining region (CDR). Additionally provided are an antibody-drug conjugate comprising the ROR1-targeting antibody or an antigen-binding fragment thereof, a preparation method therefor, and a use thereof.
L'invention concerne un anticorps ciblant ROR1, un conjugué anticorps-médicament le comprenant, un procédé de préparation correspondant et une utilisation associée. L'anticorps ciblant ROR1 ou un fragment de liaison à l'antigène de celui-ci a une région variable de chaîne lourde, une région variable de chaîne légère et une région déterminant la complémentarité (CDR). L'invention concerne en outre un conjugué anticorps-médicament comprenant l'anticorps ciblant ROR1 ou un fragment de liaison à l'antigène de celui-ci, son pr |
Author | KANG, Xiaoqiang MA, Lanping LING, Hong LAI, Shoupeng HUANG, Xiao MENG, Tao ZHANG, Peng SHEN, Jingkang WANG, Xin |
Author_xml | – fullname: LAI, Shoupeng – fullname: LING, Hong – fullname: ZHANG, Peng – fullname: WANG, Xin – fullname: HUANG, Xiao – fullname: KANG, Xiaoqiang – fullname: MENG, Tao – fullname: SHEN, Jingkang – fullname: MA, Lanping |
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DocumentTitleAlternate | 靶向ROR1的抗体、包含其的抗体偶联药物、制备方法和用途 ANTICORPS CIBLANT ROR1, CONJUGUÉ ANTICORPS-MÉDICAMENT LE COMPRENANT, PROCÉDÉ DE PRÉPARATION CORRESPONDANT ET UTILISATION ASSOCIÉE |
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Snippet | Provided are a ROR1-targeting antibody, an antibody-drug conjugate comprising same, a preparation method therefor, and a use thereof. The ROR1-targeting... |
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Title | ROR1-TARGETING ANTIBODY, ANTIBODY-DRUG CONJUGATE COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF |
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