SUBSTITUTED THIADIAZOLYL COMPOUNDS

This application is directed to inhibitors of DNA Polymerase Theta (Polθ) activity represented by the following structural formula, (I), and methods for their use, such as to treat cancer. La présente invention concerne des inhibiteurs de l'activité de l'ADN polymérase thêta (Polθ) représe...

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Main Authors BARBEAU, Xavier, GUAY, Daniel, VAISBURG, Arkadii, CARON, Antoine, LIU, Yanbin, LAPIERRE, Jean-Marc, BEN JAMAA, Abdelkhalek, ABDOLI, Abbas, TAIMOORY, Seyedeh Maryamdokht, HONG, Kwon Ho, SIMARD, Ryan
Format Patent
LanguageEnglish
French
Published 06.09.2024
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Summary:This application is directed to inhibitors of DNA Polymerase Theta (Polθ) activity represented by the following structural formula, (I), and methods for their use, such as to treat cancer. La présente invention concerne des inhibiteurs de l'activité de l'ADN polymérase thêta (Polθ) représentés par la formule structurale suivante, (I), et des procédés pour leur utilisation, par exemple pour traiter le cancer.
Bibliography:Application Number: WO2024US17461