MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS

The present invention provides novel macrocyclic aminopyridine compounds containing -O-alkylene-NH- as a linking moiety or pharmaceutically acceptable salts thereof which exhibit inhibition activity against certain mutated forms of EGFR. La présente invention concerne de nouveaux composés d'ami...

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Bibliographic Details
Main Authors LEE, Byoungmoon, JO, Yejin, SIM, Jae Young, BRYAN, Marian C, HYUN, Kwan Hoon, ROBERTSON, James Campbell, PARK, Sol, KIM, Misong, CHOI, Su Bin, KUDUK, Scott, YOON, Young Ae, LEE, Hyunjoo
Format Patent
LanguageEnglish
French
Published 29.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides novel macrocyclic aminopyridine compounds containing -O-alkylene-NH- as a linking moiety or pharmaceutically acceptable salts thereof which exhibit inhibition activity against certain mutated forms of EGFR. La présente invention concerne de nouveaux composés d'aminopyridine macrocycliques contenant-O-alkylène-NH-en tant que fraction de liaison ou des sels pharmaceutiquement acceptables de ceux-ci qui présentent une activité d'inhibition contre certaines formes mutées d'EGFR.
Bibliography:Application Number: WO2024KR02204