CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF

The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for degrading CDK2 and/or CCNE1 with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated wi...

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Bibliographic Details
Main Authors ALLEN, Bryce K, DWIGHT, Timothy A
Format Patent
LanguageEnglish
French
Published 22.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for degrading CDK2 and/or CCNE1 with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with CDK2 and/or CCNE1 with the compounds and compositions of the disclosure. La présente invention concerne de nouveaux composés et des compositions pharmaceutiques associées, et des procédés de dégradation de CDK2 et/ou CCNE1 avec les composés et les compositions de l'invention. La présente invention concerne en outre, mais de façon non limitative, des procédés de traitement de troubles associés à CDK2 et/ou à CCNE1 avec les composés et les compositions de l'invention.
Bibliography:Application Number: WO2024US15618