HETEROARYL COMPOUNDS AS PKMYT1 INHIBITORS

The present invention relates to novel heteroaryl compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, polymorphs, tautomers, atropisomers, optical and geometric isomers, prodrugs, or deuterated compounds including other possible isotopes thereof as inhibitors of PKMYT1 Th...

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Bibliographic Details
Main Authors KARCHE, Navnath Popat, PATRA, Sukanya
Format Patent
LanguageEnglish
French
Published 15.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to novel heteroaryl compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, polymorphs, tautomers, atropisomers, optical and geometric isomers, prodrugs, or deuterated compounds including other possible isotopes thereof as inhibitors of PKMYT1 The present invention also provides the process of preparation of compounds of Formula (I) for treating cancer. La présente invention concerne de nouveaux composés hétéroaryle de formule (I) et leurs sels, solvates, polymorphes, tautomères, atropisomères, isomères optiques et géométriques, promédicaments ou composés deutérés pharmaceutiquement acceptables comprenant d'autres isotopes possibles de ceux-ci, en tant qu'inhibiteurs de PKMYT1. La présente invention concerne également le procédé de préparation de composés de formule (I) pour le traitement du cancer.
Bibliography:Application Number: WO2024IN50118