NOVEL COMPOUND AS LYSYL-TRNA SYNTHETASE 1 INHIBITOR, AND USE THEREOF

The present invention relates to a novel compound as a lysyl-tRNA synthetase 1 (KARS1) inhibitor, and a use thereof, and, more specifically, to a novel compound as a lysyl-tRNA synthetase 1 inhibitor, and a use of preventing or treating immune cell migration-associated diseases and cancer metastasis...

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Bibliographic Details
Main Authors PARK, Choul Hong, KWON, Hyuk Sang, ROH, Chae Woon, OH, Jin Soo, KWON, Nam Hoon
Format Patent
LanguageEnglish
French
Korean
Published 02.08.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention relates to a novel compound as a lysyl-tRNA synthetase 1 (KARS1) inhibitor, and a use thereof, and, more specifically, to a novel compound as a lysyl-tRNA synthetase 1 inhibitor, and a use of preventing or treating immune cell migration-associated diseases and cancer metastasis. La présente invention concerne un nouveau composé utilisé en tant qu'inhibiteur de lysyl-ARNt synthétase 1 (KARS1), et son utilisation, et, plus particulièrement, un nouveau composé utilisé en tant qu'inhibiteur de lysyl-ARNt synthétase 1, et une utilisation dans la prévention ou le traitement de maladies associées à la migration de cellules immunitaires et de métastases cancéreuses. 라이실-tRNA 합성효소 1(lysyl-tRNA synthetase 1, KARS1) 저해제로서의 신규 화합물 및 이의 용도에 관한 것으로, 보다 상세하게는 라이실-tRNA 합성효소 1 저해제로서의 신규 화합물 및 이의 면역세포 이동 관련 질환 및 암 전이 예방 또는 치료 용도에 관한 것이다.
Bibliography:Application Number: WO2024KR01237