RNA-DIRECTED PROTEASE SYSTEMS AND USES THEREOF

Provided herein are compositions, systems, and methods comprising effector proteins, and uses thereof. These effector proteins may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure may leverage the activities of these effector...

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Bibliographic Details
Main Authors CHAIKIND, Brian R, ABBOTT, Timothy Robert
Format Patent
LanguageEnglish
French
Published 11.07.2024
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Summary:Provided herein are compositions, systems, and methods comprising effector proteins, and uses thereof. These effector proteins may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure may leverage the activities of these effector proteins for such applications as detecting genetic mutations and treating various diseases and disorders. L'invention concerne des compositions, des systèmes et des méthodes comprenant des protéines effectrices et leurs utilisations. Ces protéines effectrices peuvent être caractérisées en tant que protéines associées à CRISPR (Cas). Divers compositions, systèmes et méthodes de la présente invention peuvent tirer profit des activités de ces protéines effectrices pour de telles applications en tant que détection de mutations génétiques et traitement de divers maladies et troubles.
Bibliography:Application Number: WO2024US10545