MULTIVALENT ASSEMBLIES FOR ENHANCED TARGET HYBRIDIZATION

Multivalent assemblies for target hybridization are described. The multivalent assemblies include oligonucleotide sets that hybridize to a target nucleic acid to permit capture of the target nucleic acid. In an embodiment, the multivalent assemblies are heteromultivalent such that the oligonucleotid...

Full description

Saved in:
Bibliographic Details
Main Authors SHULTZABERGER, Sarah E, FISHER, Jeffrey, SLATTER, Andrew, BRODIN, Jeffrey, RANDISE-HINCHLIFF, Carlo, STORMS, Lena, KARADEEMA, Rebekah
Format Patent
LanguageEnglish
French
Published 27.06.2024
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:Multivalent assemblies for target hybridization are described. The multivalent assemblies include oligonucleotide sets that hybridize to a target nucleic acid to permit capture of the target nucleic acid. In an embodiment, the multivalent assemblies are heteromultivalent such that the oligonucleotide sets include different oligonucleotides that bind to different regions of the target nucleic acid. L'invention concerne des ensembles multivalents pour l'hybridation de cible. Les ensembles multivalents comprennent des ensembles oligonucléotidiques qui s'hybrident à un acide nucléique cible pour permettre la capture de l'acide nucléique cible. Dans un mode de réalisation, les ensembles multivalents sont hétéromères de telle sorte que les ensembles oligonucléotidiques comprennent différents oligonucléotides qui se lient à différentes régions de l'acide nucléique cible.
Bibliography:Application Number: WO2023US84945