INHIBITORS OF JAK2

The present invention is directed to the compounds of Formula (I) - inhibitors JAK2. The inhibitors described herein can be useful in the treatment of diseases or disorders associated with JAK2, such as blood diseases. In particular, the invention is concerned with compounds and pharmaceutical compo...

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Bibliographic Details
Main Authors ABAGYAN, Ruben, REZEKIN, Igor, KHVAT, Alexander, SAVCHUK, Nikolay
Format Patent
LanguageEnglish
French
Published 25.07.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention is directed to the compounds of Formula (I) - inhibitors JAK2. The inhibitors described herein can be useful in the treatment of diseases or disorders associated with JAK2, such as blood diseases. In particular, the invention is concerned with compounds and pharmaceutical compositions inhibiting JAK2, methods of treating diseases or disorders associated with JAK2, and methods of synthesizing these compounds. La présente invention concerne les composés de formule (I) comme inhibiteurs JAK2. Les inhibiteurs décrits ici peuvent être utiles dans le traitement de maladies ou de troubles associés à JAK2, tels que des hémopathies. En particulier, l'invention concerne des composés et des compositions pharmaceutiques inhibant JAK2, des méthodes de traitement de maladies ou de troubles associés à JAK2, et des méthodes de synthèse de ces composés.
Bibliography:Application Number: WO2023US84697