PRODRUGS OF DIMETHYLTRYPTAMINE AND DERIVATIVES THEREOF

Provided herein are compounds of Formula (I-A), Formula (I-B), Formula (II-A), Formula (II-B), pharmaceutically acceptable salts thereof, and compositions thereof, wherein R1, R2, R3, R7, R8, R9, R10, R11, R12, R13, R14, A, B, E, W, X, and n are defined herein. The disclosed compounds are useful for...

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Bibliographic Details
Main Authors KHAN, Tanweer A, GIBBS, Alan C, PERNI, Robert B
Format Patent
LanguageEnglish
French
Published 18.07.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are compounds of Formula (I-A), Formula (I-B), Formula (II-A), Formula (II-B), pharmaceutically acceptable salts thereof, and compositions thereof, wherein R1, R2, R3, R7, R8, R9, R10, R11, R12, R13, R14, A, B, E, W, X, and n are defined herein. The disclosed compounds are useful for treating various diseases, including depression and associated conditions. L'invention concerne des composés de formule (I-A), de formule (I-B), de formule (II-A), de formule (II-B), des sels pharmaceutiquement acceptables de ceux-ci, et des compositions de ceux-ci, R1, R2, R3, R7, R8, R9, R10, R11, R12, R13, R14, A, B, E, W, X, et n étant définis dans la description. Les composés divulgués sont utiles pour traiter diverses maladies, notamment la dépression et des pathologies associées.
Bibliography:Application Number: WO2023US84319