EFFICIENT AND SCALABLE SUSPENSION IPSC CULTURE SYSTEM COMPLIANT WITH GOOD MANUFACTURING PRACTICES

• Main Authors: MARTIN-IBANEZ, Raquel, LEE, Hojae, SAREEN, Dhruv
• Format: Patent
• Language: English; French
• Published: 13.06.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Described herein are cGMP methods of iPSC adaptation and culturing in suspension culture. Also described are iPSC expansion methods in suspension culture. Various embodiments provide for a method of adapting adherent induced pluripotent stem cells (iPSCs) to suspension iPSCs, comprising: (i) seeding...