PROGESTERONE PHARMACEUTICAL COMPOSITION

• Main Authors: SHEN, Jialin, YING, Shengjun, DONG, Yongfeng, YING, Zichao, ZHANG, Xiaoming, SHEN, Zhiqun, FU, Enjun
• Format: Patent
• Language: Chinese; English; French
• Published: 13.06.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A progesterone pharmaceutical composition. Specifically, provided is an oral formulation, comprising (a) progesterone; (b) an agent for promoting progesterone bio-utilization; and (c) a pharmaceutically acceptable oral formulation carrier. The agent for promoting progesterone bio-utilization is selected from one or more of sucrose fatty acid esters. The oral formulation is high in bioavailability and low in side effects, making it a superior progesterone oral product. L'invention concerne une composition pharmaceutique de progestérone. Spécifiquement, l'invention concerne une formulation orale, comprenant (a) de la progestérone ; (b) un agent pour favoriser la bio-utilisation de la progestérone ; et (c) un support de formulation orale pharmaceutiquement acceptable. L'agent favorisant la bio-utilisation de la progestérone est choisi parmi un ou plusieurs esters d'acide gras de saccharose. La formulation orale présente une biodisponibilité élevée et des effets secondaires faibles, ce qui permet d'obtenir un pro