PEPTIDE HAVING ACTIVITY OF SKIN WHITENING AND USES THEREOF

• Main Authors: LEE, Eung Ji, JUNG, Da Won, JEONG, Min Kyeong, CHUNG, Yong Ji, KIM, Eun Mi
• Format: Patent
• Language: English; French; Korean
• Published: 23.05.2024
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

A peptide of the present invention has activity of skin whitening by inhibiting the incorporation of melanosome in keratinocytes and promoting the degradation of melanosomes. The peptide of the present invention can be used as an active ingredient in drugs for the treatment or prevention of hyperpigmentation diseases caused by the deposition of excessive melanosome, or as an effective ingredient in cosmetics for skin whitening. La présente invention concerne un peptide ayant une activité de blanchiment de la peau par inhibition de l'incorporation de mélanosome dans les kératinocytes et la promotion de la dégradation des mélanosomes. Le peptide selon la présente invention peut être utilisé en tant que principe actif dans des médicaments pour le traitement ou la prévention de maladies d'hyperpigmentation provoquées par le dépôt excessif de mélanosome ou en tant que principe actif dans des produits cosmétiques pour le blanchiment de la peau. 본 발명의 펩타이드는 각질형성세포에서 멜라노좀의 함입을 억제하고, 멜라노좀의 분해를 촉진함으로써, 피부 미백활성을 갖는다. 본 발명의 펩타이드는 과도한 멜라노좀의 침착으로 인해 발생한 과다색소침착 질환의 치료 또는 예방용 약물의 활성성분 또는 피부미백용 화장료의 유효성분으로 사용될 수 있다.