CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS

Provided herein, in some aspects, are methods and compositions for cell conversion. The methods may convert a cell population comprising one cell type to another cell population comprising another cell type. The converted cell types may have increased cell differentiation potential. The converted ce...

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Bibliographic Details
Main Authors DENG, Hongkui, GUAN, Jingyang, WANG, Guan, ZHANG, Zhengyuan, WANG, Jinlin, HE, Huanjing, ZHONG, Xinxing, WANG, Yanglu
Format Patent
LanguageEnglish
French
Published 18.04.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided herein, in some aspects, are methods and compositions for cell conversion. The methods may convert a cell population comprising one cell type to another cell population comprising another cell type. The converted cell types may have increased cell differentiation potential. The converted cell types can comprise pluripotent stem cells. The compositions provided herein may comprise chemical reprogramming factors for converting cells. The compositions provided herein may comprise chemical reprogramming factors and cells. Also provided herein are reagents for carrying out the methods for converting cells. Additionally, provided herein are methods and compositions for using various cell types obtained by the methods and/or compositions provided herein. Selon certains aspects, l'invention concerne des procédés et des compositions pour la conversion de cellules. Les procédés peuvent convertir une population de cellules comprenant un type de cellule en une autre population de cellules comprenant un autre type de cellule. Les types de cellules convertis peuvent avoir un potentiel de différenciation cellulaire accru. Les types de cellules convertis peuvent comprendre des cellules souches pluripotentes. Les compositions de l'invention peuvent comprendre des facteurs de reprogrammation chimique pour convertir des cellules. Les compositions de l'invention peuvent comprendre des facteurs de reprogrammation chimique et des cellules. L'invention concerne également des réactifs pour la mise en oeuvre des procédés de conversion de cellules. De plus, l'invention concerne des procédés et des compositions pour utiliser divers types de cellules obtenus selon les procédés et/ou les compositions de l'invention.
Bibliography:Application Number: WO2023CN113080