NOVEL TRICYCLIC HETEROCYCLIC CARBALDEHYDE COMPOUND AND PHARMACEUTICAL COMPOSITION, CONTAINING SAME, FOR IRE1α INHIBITION

• Main Authors: KIM, Min Jeong, KIM, Ji Sook, PARK, Won Gi, JUNG, Seung Hyun, CHOI, Jae Yul, AHN, Young Gil
• Format: Patent
• Language: English; French; Korean
• Published: 04.04.2024
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a novel tricyclic heterocyclic carbaldehyde compound and a pharmaceutical composition, containing same, for IRE1α inhibition and, more specifically, to a novel tricyclic heterocyclic carbaldehyde compound and a pharmaceutical composition, containing same, for treatment or prevention of IRE1α-related diseases. La présente invention concerne un nouveau composé carbaldéhyde hétérocyclique tricyclique et une composition pharmaceutique le contenant, pour l'inhibition de l'IRE1α et, plus spécifiquement, un nouveau composé carbaldéhyde hétérocyclique tricyclique et une composition pharmaceutique le contenant, pour le traitement ou la prévention de maladies liées à l'IRE1α. 본 발명은 신규한 삼환식 헤테로고리 카바알데히드 화합물 및 이를 포함하는 IRE1α 저해를 위한 약학적 조성물에 관한 것으로, 보다 구체적으로는 IRE1α 관련 질환을 치료 또는 예방하기 위한 신규한 삼환식 헤테로고리 카바알데히드 화합물 및 이를 포함하는 약학적 조성물에 관한 것이다.