METHOD FOR ACCELERATING MOLECULAR COMPUTATION USING NUCLEIC ACID CONDENSATES

The present invention relates to a method for accelerating molecular computation using nucleic acid condensates and, more specifically, to a method for accelerating molecular computation using nucleic acid condensates, the method being designed such that nucleic acid condensates are produced by link...

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Bibliographic Details
Main Authors LEE, Chan Seok, SHIN, Yong Dae, KIM, Do Nyun, DO, Sung Ho
Format Patent
LanguageEnglish
French
Korean
Published 04.04.2024
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Summary:The present invention relates to a method for accelerating molecular computation using nucleic acid condensates and, more specifically, to a method for accelerating molecular computation using nucleic acid condensates, the method being designed such that nucleic acid condensates are produced by linking together a plurality of nucleic acid scaffolds having client-binding portions in a solution phase, and by making molecular computation elements to exist at a high concentration in the nucleic acid condensates, a nucleic acid strand displacement reaction between the molecular computation elements can occur with a higher probability. La présente invention concerne un procédé pour accélérer le calcul moléculaire au moyen de condensats d'acide nucléique et, plus particulièrement, un procédé d'accélération de calcul moléculaire au moyen de condensats d'acide nucléique, conçu de sorte que des condensats d'acide nucléique soient produits en reliant une pluralité d'échafaudages d'acide nucléique ayant des parties de liaison au client dans une phase de solution, et en faisant en sorte que des éléments de calcul moléculaire soient présents à une concentration élevée dans les condensats d'acide nucléique, une réaction de déplacement de brin d'acide nucléique entre les éléments de calcul moléculaire pouvant se produire avec une probabilité plus élevée. 본 발명은 핵산 응집체를 이용한 분자 연산 가속화 방법에 관한 것으로서, 보다 상세하게는 클라이언트 결합부를 갖는 복수의 핵산 스캐폴드를 용액 상에서 상호 결합시켜 핵산 응집체를 제조하고 이 핵산 응집체 내에 분자 연산 요소들이 고농도로 존재하도록 함으로써 분자 연산 요소들 사이의 핵산 가닥 치환 반응이 보다 높은 확률로 일어날 수 있도록 설계된, 핵산 응집체를 이용한 분자 연산 가속화 방법에 관한 것이다.
Bibliography:Application Number: WO2023KR14903