HUMANIZED ANTIBODIES AGAINST NECTIN-4 AND DRUG CONJUGATES THEREOF

The present invention provides humanized antibodies against Nectin-4 and antibody drug conjugates (ADCs) of the humanized antibodies and use thereof in treating diseases, in particular cancer. La présente invention concerne des anticorps humanisés dirigés contre la nectine-4 et des conjugués anticor...

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Bibliographic Details
Main Authors VITENSHTEIN, Alon, CINAMON, Guy, TSUKERMAN, Pinchas, ATIEH, Anas, OBIEDAT, Akram
Format Patent
LanguageEnglish
French
Published 28.03.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides humanized antibodies against Nectin-4 and antibody drug conjugates (ADCs) of the humanized antibodies and use thereof in treating diseases, in particular cancer. La présente invention concerne des anticorps humanisés dirigés contre la nectine-4 et des conjugués anticorps-médicament (ADC) des anticorps humanisés, ainsi qu'une utilisation associée dans le traitement de maladies, en particulier de cancer.
Bibliography:Application Number: WO2023IL51016