USE OF PREVOTELLA IN PREVENTION AND TREATMENT OF ATTENTION DEFICIT-HYPERACTIVITY DISORDER

• Main Authors: GUO, Zhangxin, ZOU, Zhen, QIU, Jingfu, CHEN, Chengzhi, LIU, Yiyun
• Format: Patent
• Language: Chinese; English; French
• Published: 28.03.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present invention provides use of Prevotella in the prevention and treatment of attention deficit-hyperactivity disorder. The Prevotella is used at a therapeutically effective amount to achieve the treatment of attention deficit-hyperactivity disorder. The strain number of the Prevotella is JCM 13464 = DSM 18205. The Prevotella has a quite significant effect on the improvement of a hyperactive behavior, a spontaneous activity level, and an impulsive behavior. The Prevotella can significantly increase levels of adrenocorticotropic hormone and cortisol in serum, improve the dysfunction of a neuroendocrine system, and significantly increase the gene expression of a glucocorticoid receptor (Nr3c1) and a mineralocorticoid receptor (Nr3c2), thereby alleviating the social dysfunction of ADHD. La présente invention concerne l'utilisation de la Prevotella dans la prévention et le traitement d'un trouble d'hyperactivité avec déficit de l'attention. La Prevotella est utilisée à une quantité thérapeutiquement efficac