IMPROVEMENTS TO NEXT-GENERATION TARGET ENRICHMENT PERFORMANCE

The present disclosure is directed to compositions and kits for PCR amplification. The present disclosure is also directed to methods of amplifying nucleic acid molecules to improve upon uniformity of coverage and/or to reduce GC bias during downstream sequencing operations. La présente invention co...

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Bibliographic Details
Main Authors GODWIN, Brian Christopher, LIN, Junyan, XI, Liu, VAN DER MERWE, Ruben Gerhard, WU, Beijing, FURTADO, Nitya Margaret, CRARY-DOOLEY, Florence Katharine, LI, Jingchuan
Format Patent
LanguageEnglish
French
Published 07.03.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Summary:The present disclosure is directed to compositions and kits for PCR amplification. The present disclosure is also directed to methods of amplifying nucleic acid molecules to improve upon uniformity of coverage and/or to reduce GC bias during downstream sequencing operations. La présente invention concerne des compositions et des kits pour l'amplification par PCR. La présente invention concerne également des procédés d'amplification de molécules d'acide nucléique visant à améliorer l'uniformité de la couverture et/ou à réduire le biais GC pendant les opérations de séquençage en aval.
Bibliography:Application Number: WO2023EP73555