2-AZA- AND 2-OXABICYCLO[2.1.1]HEXANE DERIVATIVES AS FACTOR XIIA ENZYME INHIBITORS

The present invention provides compounds of formula (I): Formula (I) compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, V, Z, Y and B are as defined herein. La présente invention concerne des composés de...

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Main Authors NORTH, Carl Leslie, FROMONT, Christophe, GREVES, William Jack, CAMP, Nicholas Paul, EVANS, David Michael, KEITA, Massaba, POMEROLE, Julien, JOHNSTONE, Shawn Donald, DAVIE, Rebecca Louise, EDWARDS, Hannah Joy, BARTHOLOMEUS, Johan
Format Patent
LanguageEnglish
French
Published 22.02.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of formula (I): Formula (I) compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, V, Z, Y and B are as defined herein. La présente invention concerne des composés de formule (I) : Des compositions comprenant de tels composés ; l'utilisation de tels composés en médecine ; et des méthodes de traitement de patients avec de tels composés ; A, W, V, Z, Y et B étant tels que définis dans la description.
Bibliography:Application Number: WO2023GB52166