ANTI-TFR:PAYLOAD FUSIONS AND METHODS OF USE THEREOF

• Main Authors: GAO, Min, ZHANG, Bojie, KEATING, Nicole, AIMÉ-WILSON, Pascaline, CYGNAR, Katherine, PRAGGASTIS, Maria, DUGAN, John, BABB, Robert
• Format: Patent
• Language: English; French
• Published: 21.03.2024
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Provided, in part, are an anti-human transferrin receptor antigen-binding proteins and fusion proteins comprising an anti-human transferrin receptor antigen-binding proteins (e.g., in scFv, Fab or antibody format) which may be fused to a payload for delivery of the payload to a targeted tissue (e.g....