THERAPEUTIC AGENT FOR MENISCUS

Provided are: a pharmaceutical composition for treating damage to the white-white zone or red-white zone of the meniscus, said composition containing an HMGB1 fragment peptide containing an amino acid sequence delimited by SEQ ID NO 1, or a variant thereof; and a pharmaceutical composition for treat...

Full description

Saved in:
Bibliographic Details
Main Authors TAMAI, Katsuto, YAMAZAKI, Takehiko, ISHIBASHI, Kyota, SHIMBO, Takashi
Format Patent
LanguageEnglish
French
Japanese
Published 04.01.2024
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:Provided are: a pharmaceutical composition for treating damage to the white-white zone or red-white zone of the meniscus, said composition containing an HMGB1 fragment peptide containing an amino acid sequence delimited by SEQ ID NO 1, or a variant thereof; and a pharmaceutical composition for treating a meniscus excision site, said composition containing an HMGB1 fragment peptide containing an amino acid sequence delimited by SEQ ID NO 1, or a variant thereof. L'invention concerne : une composition pharmaceutique pour traiter une lésion de la zone blanc-blanc ou de la zone rouge-blanc du ménisque, ladite composition contenant un peptide de fragment HMGB1 contenant une séquence d'acides aminés délimitée par la SEQ ID NO 1, ou un variant de celle-ci ; et une composition pharmaceutique pour traiter un site d'excision de ménisque, ladite composition contenant un peptide de fragment HMGB1 contenant une séquence d'acides aminés délimitée par la SEQ ID NO 1, ou un variant de celle-ci. 配列番号:1に記載のアミノ酸配列を含むHMGB1断片ペプチドまたはその変異体を含む、半月板におけるwhite-white zoneまたはred-white zoneの損傷を治療するための医薬組成物、ならびに配列番号:1に記載のアミノ酸配列を含むHMGB1断片ペプチドまたはその変異体を含む、半月板の切除部位を治療するための医薬組成物が提供される。
Bibliography:Application Number: WO2023JP24150