N-SUBSTITUTED INDOLE DERIVATIVES AND CONJUGATES FOR THE TREATMENT OF CANCER

The present invention relates to N-substituted derivatives of indoles of formula (I): and their use in the treatment of cancer. The invention further provides protein-drug conjugates, more particularly antibody-drug conjugates, from compounds of formula (I). La présente invention concerne des dérivé...

Full description

Saved in:
Bibliographic Details
Main Authors BRIDON, Dominique, BOUGERET, Cécile, CARNIATO, Denis
Format Patent
LanguageEnglish
French
Published 04.01.2024
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to N-substituted derivatives of indoles of formula (I): and their use in the treatment of cancer. The invention further provides protein-drug conjugates, more particularly antibody-drug conjugates, from compounds of formula (I). La présente invention concerne des dérivés d'indoles N-substitués représentés par la formule (I) : et leur utilisation dans le traitement du cancer. L'invention concerne en outre des conjugués protéine-médicament, plus particulièrement des conjugués anticorps-médicament, obtenus à partir de composés de formule (I).
Bibliography:Application Number: WO2023EP67379