COMPOSITION FOR PREPARING MULTI-CROSSLINKED TEMPERATURE-SENSITIVE HYDROGEL, AND USE THEREOF

• Main Authors: LEE, Soo Hee, CHA, Mi Sun, KIM, Su Hee
• Format: Patent
• Language: English; French; Korean
• Published: 12.01.2023
• Subjects: BANDAGES, DRESSINGS OR ABSORBENT PADS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FILTERS IMPLANTABLE INTO BLOOD VESSELS; FIRST-AID KITS; FOMENTATION; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; PROSTHESES; THEIR PREPARATION OR CHEMICAL WORKING-UP; TREATMENT OR PROTECTION OF EYES OR EARS; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS

The present application relates to a composition for preparing a temperature-sensitive hydrogel and to a use thereof, and provides a temperature-sensitive hydrogel composition and a method for preparing a temperature-sensitive hydrogel composition by using same composition, the temperature-sensitive hydrogel composition comprising: a first agent of a liquid formulation including an aqueous solution containing chitosan and phosphate ion; and an aqueous solution containing 0.05-3.5% by weight of chitosan and 0.1-40% by weight of phosphate ion with respect to the total weight of the first agent composition. La présente demande se rapporte à une composition pour la préparation d'hydrogel sensible à la température et à son utilisation, et concerne une composition d'hydrogel sensible à la température et un procédé de préparation d'une composition d'hydrogel sensible à la température à l'aide de la même composition, la composition d'hydrogel sensible à la température comprenant : un premier agent d'une formulation liquide comprenant une solution aqueuse contenant du chitosane et un ion phosphate ; et une solution aqueuse contenant de 0,05 à 3,5 % en poids de chitosane et de 0,1 à 40 % en poids d'ion phosphate par rapport au poids total de la première composition d'agent. 본 출원은 온도감응성 하이드로겔 제조용 조성물 및 이의 용도에 관한 것으로서, 키토산 및 인산 이온이 함유된 수용액을 포함하는 액상 제형의 1제를 포함하며, 상기 1제 조성물 전체 중량에 대하여, 0.05 내지 3.5 중량%의 키토산, 0.1 내지 40 중량%의 인산 이온이 함유된 수용액을 포함하는 온도감응성 하이드로겔 조성물, 및 상기 조성물을 이용한 온도감응성 하이드로겔 조성물을 제조하는 방법을 제공한다.