PH-RESPONSIVE LIPID DERIVATIVE
The present invention provides: a pH-responsive lipid derivative represented by the structure shown in a formula (i) (where each symbol in the formula is as defined in the description); and a pH-responsive carrier that is useful as a carrier for safely and efficiently delivering a low-molecular-weig...
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Main Authors | , , , , , , , , , , |
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Format | Patent |
Language | English French Japanese |
Published |
12.01.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides: a pH-responsive lipid derivative represented by the structure shown in a formula (i) (where each symbol in the formula is as defined in the description); and a pH-responsive carrier that is useful as a carrier for safely and efficiently delivering a low-molecular-weight drug and the like to tumor tissue.
La présente invention concerne : un dérivé lipidique sensible au pH représenté par la structure représentée dans la formule (i) (chaque symbole dans la formule étant tel que défini dans la description) ; et un support sensible au pH qui est utile en tant que support pour l'administration sûre et efficace d'un médicament à faible poids moléculaire et similaire au tissu tumoral.
本発明は、下記式(i)で表される構造:(上記式中、各記号は明細書に記載のとおりである。) で表されるpH応答性脂質誘導体、および腫瘍組織への低分子薬剤等の送達等を、安全かつ効率よく行うための輸送担体として有用なpH応答性輸送担体を提供する。 |
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Bibliography: | Application Number: WO2022JP26863 |