PURIFICATION PROCESS FOR PHARMACEUTICAL EXCIPIENT

The present invention relates to a method for decreasing the level of nitrite and other nitrosating agents in a pharmaceutical excipient such as microcrystalline cellulose by exposing the excipient to a flow of air with a relative humidity of at least 5%. La présente invention concerne un procédé po...

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Bibliographic Details
Main Authors CARMODY, Alan Francis, O'CONNOR, Garry, SCRIVENS, Garry
Format Patent
LanguageEnglish
French
Published 23.11.2023
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:The present invention relates to a method for decreasing the level of nitrite and other nitrosating agents in a pharmaceutical excipient such as microcrystalline cellulose by exposing the excipient to a flow of air with a relative humidity of at least 5%. La présente invention concerne un procédé pour diminuer le taux de nitrite et d'autres agents de nitrosation dans un excipient pharmaceutique, tel que la cellulose microcristalline, en exposant l'excipient à un écoulement d'air ayant une humidité relative d'au moins 5 %.
Bibliography:Application Number: WO2023IB54934