BIOELECTRONIC SMART BANDAGE FOR CONTROLLING WOUND PH THROUGH PROTON DELIVERY

• Main Authors: SELBERG, John, TEBYANI, Maryam, BANIYA, Prabhat, TEODORESCU, Mircea, PANSODTEE, Pattawong, ASEFIFEYZABADI, Narges, NGUYEN, Tiffany, ROLANDI, Marco
• Format: Patent
• Language: English; French
• Published: 14.12.2023
• Subjects: BLASTING; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; ELECTROTHERAPY; HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA; HEATING; HUMAN NECESSITIES; HYGIENE; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; LIGHTING; MAGNETOTHERAPY; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MECHANICAL ENGINEERING; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PHYSICS; POSITIVE DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS; RADIATION THERAPY; ULTRASOUND THERAPY; WEAPONS

A bioelectronic smart device capable of charge (e.g., proton) delivery for providing treatment (e.g., changing the pH) of wound surfaces on in vitro and in vivo models. In one example, this is achieved through the use of a device that incorporates a hydrogel-based ion pump with a custom PCB for pump actuation. In one example, we were able to achieve delivery of approximately 6-19 nanomoles of protons to in vivo wound surfaces after ten minutes. Un bandage intelligent capable de distribuer de multiples ions/produits biochimiques pour des applications de cicatrisation de plaie. Dans un ou plusieurs exemples, une commande de détection et d'actionnement en boucle fermée est obtenue.