COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING INFLAMMATORY DISEASES, ALLERGIC DISEASES, OR SEPSIS COMPRISING GLUCOPYRANOSIDE DERIVATIVES

• Main Authors: KWAK, Ji Yun, NGUYEN, Thi Minh Nguyet
• Format: Patent
• Language: English; French; Korean
• Published: 05.10.2023
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SUGARS

The present invention relates to a composition for preventing, ameliorating, or treating inflammatory diseases, allergic diseases, or sepsis. As a composition that inhibits the expression or activity of pro-inflammatory cytokines IL-8 or TNF-α, inhibits degranulation of mast cells, and has an effect of ameliorating symptoms caused by sepsis, the composition according to one aspect can be effectively used for preventing, ameliorating, or treating inflammatory diseases, allergic diseases, or sepsis. La présente invention concerne une composition pour prévenir, soulager ou traiter des maladies inflammatoires, des maladies allergiques ou la sepsie. Selon un aspect, la composition inhibant l'expression ou l'activité de cytokines pro-inflammatoires IL-8 ou TNF-α, inhibe la dégranulation des mastocytes et a un effet d'atténuation des symptômes provoqués par la sepsie et peut être utilisée de manière efficace pour prévenir, soulager ou traiter des maladies inflammatoires, des maladies allergiques ou la sepsie. 염증성 질환, 알레르기성 질환 또는 패혈증 예방, 개선 또는 치료용 조성물에 관한 것으로, 일 양상에 따른 조성물은 전염증성 사이토카인 IL-8 또는 TNF-α의 발현 또는 활성을 억제하고, 비만세포의 탈과립화를 억제하며, 패혈증에 의한 증상에 대한 개선 효과가 있어, 염증성 질환, 알레르기성 질환 또는 패혈증의 예방, 개선 또는 치료에 유용하게 사용될 수 있다.