BIOMARKERS AND METHOD FOR DETECTING STATIN INTOLERANCE IN PATIENTS WITH CARDIOVASCULAR RISK

• Main Authors: BONET MARTÍNEZ, Fernando, TORO CEBADA, Rocio, MANGAS ROJAS, Alipio
• Format: Patent
• Language: English; French; Spanish
• Published: 05.10.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Disclosed are biomarkers that allow statin intolerance to be diagnosed in patients with cardiovascular risk, which is formed by a panel of miRNAs and clinical variables. Also disclosed are a method for detecting statin intolerance, a kit or device, and uses. Biomarcadores que permiten diagnosticar la intolerancia a estatinas en pacientes con riesgo cardiovascular, constituido por un panel de miARNs y variables clínicas, método para la detección de intolerantes a estatinas, kit o dispositivo y usos. Biomarqueurs qui permettent de diagnostiquer l'intolérance aux statines chez des patients présentant un risque cardiovasculaire, constitué d'un ensemble de miARN et de variables cliniques, méthode de détection de personnes intolérantes aux statines, kit ou dispositif et utilisations.