TREATMENTS FOR SINGLE-MUTANT WALDENSTRÖM'S MACROGLOBULINEMIA

The present invention relates to methods of treating cancer, in which a CXCR4 inhibitor such as mavorixafor (X4P-001) or a pharmaceutically acceptable salt thereof or pharmaceutical composition thereof is administered in combination with an additional therapeutic agent, such as a BTK or BCL-2 inhibi...

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Bibliographic Details
Main Authors TAVERAS, Art, NGUYEN, Chi
Format Patent
LanguageEnglish
French
Published 14.09.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to methods of treating cancer, in which a CXCR4 inhibitor such as mavorixafor (X4P-001) or a pharmaceutically acceptable salt thereof or pharmaceutical composition thereof is administered in combination with an additional therapeutic agent, such as a BTK or BCL-2 inhibitor or a BH3 mimetic. La présente invention concerne des méthodes de traitement du cancer, dans lesquelles un inhibiteur de CXCR4 tel que le mavorixafor (X4P-001) ou un sel pharmaceutiquement acceptable de celui-ci ou une composition pharmaceutique de celui-ci est administré en combinaison avec un agent thérapeutique supplémentaire, tel qu'un inhibiteur de BTK ou BCL-2 ou un mimétique de BH3.
Bibliography:Application Number: WO2023US14834