A METHOD FOR DIAGNOSIS OF TRAUMATIC BRAIN INJURY

The present disclosure relates to in vitro methods for diagnosing traumatic brain injury (TBI), in particular to methods wherein the diagnosis is based on determining level of glycan-based biomarkers in saliva and/or urine of a subject suspected to suffer from TBI. The disclosure also relates to use...

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Bibliographic Details
Main Authors VÄLIMAA, Lasse, HAREL, Adrian, HAAVISTO, Oskar, KVIST, Mårten
Format Patent
LanguageEnglish
French
Published 31.08.2023
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The present disclosure relates to in vitro methods for diagnosing traumatic brain injury (TBI), in particular to methods wherein the diagnosis is based on determining level of glycan-based biomarkers in saliva and/or urine of a subject suspected to suffer from TBI. The disclosure also relates to use of specific N-glycans as biomarkers of TBI in saliva and urine. La présente divulgation concerne des méthodes in vitro pour diagnostiquer un traumatisme crânio-cérébral (TBI), en particulier des méthodes dans lesquelles le diagnostic est basé sur la détermination du niveau de biomarqueurs à base de glycane dans la salive et/ou l'urine d'un sujet suspecté de souffrir de TBI. La divulgation concerne également l'utilisation de N-glycanes spécifiques en tant que biomarqueurs de TBI dans la salive et l'urine.
Bibliography:Application Number: WO2023FI50076