METHODS OF TREATMENT FOR CYSTIC FIBROSIS

This disclosure provides methods of treating cystic fibrosis or a CFTR-mediated disease comprising administering Compound I, a deuterated derivative thereof, or a pharmaceutically acceptable salt of any of the foregoing. The disclosure also provides pharmaceutical compositions comprising Compound I,...

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Bibliographic Details
Main Authors LATERREUR, Julie, LU, Jennifer, BOREK, Bartlomiej
Format Patent
LanguageEnglish
French
Published 10.08.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This disclosure provides methods of treating cystic fibrosis or a CFTR-mediated disease comprising administering Compound I, a deuterated derivative thereof, or a pharmaceutically acceptable salt of any of the foregoing. The disclosure also provides pharmaceutical compositions comprising Compound I, a deuterated derivative thereof, or a pharmaceutically acceptable salt of any of the foregoing, and optionally comprising one or more additional CFTR-modulating agents. La présente divulgation concerne des méthodes de traitement de la fibrose kystique ou d'une maladie médiée par CFTR comprenant l'administration du composé I, d'un dérivé deutéré de celui-ci, ou d'un sel pharmaceutiquement acceptable de l'un quelconque des précédents. L'invention concerne également des compositions pharmaceutiques comprenant le composé I, un dérivé deutéré de celui-ci, ou un sel pharmaceutiquement acceptable de l'un quelconque des précédents, et comprenant éventuellement un ou plusieurs agents modulateurs de CFTR supplémentaires.
Bibliography:Application Number: WO2023US12230