CELL SHEET

• Main Authors: TAMAI, Katsuto, YAMAZAKI, Takehiko, TAMAKOSHI, Tomoki, KIKUCHI, Yasushi
• Format: Patent
• Language: English; French; Japanese
• Published: 27.07.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

The present disclosure relates to a cell sheet to be transplanted into the skin of a patient of epidermolysis bullosa dystrophica. This cell sheet is composed of cells collected from the body fluid in blisters of a patient of epidermolysis bullosa dystrophica. A type VII collagen gene is introduced into the cells. La présente invention concerne un film cellulaire à transplanter dans la peau d'un patient atteint d'épidermolyse bulleuse dystrophique. Ce film cellulaire est composé de cellules collectées à partir du fluide corporel présent dans les vésicules d'un patient atteint d'épidermolyse bulleuse dystrophique. Un gène de collagène de type VII est introduit dans les cellules. 本開示は、栄養障害型表皮水疱症の患者の皮膚に移植される細胞シートに関する。この細胞シートは、栄養障害型表皮水疱症の患者の水疱内の体液から採取された細胞で構成される。この細胞には、VII型コラーゲン遺伝子が導入されている。