COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING METABOLIC DISEASES, CONTAINING EXTRACT OF LYSIMACHIA MAURITIANA AS ACTIVE INGREDIENT

• Main Authors: SUNG, Yoon-Young, KIM, Dong-Seon, YUK, Heung Joo, KIM, Young Sook, LEE, Yun Mi, SON, Eun Jung
• Format: Patent
• Language: English; French; Korean
• Published: 06.07.2023
• Subjects: FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The present invention relates to a composition which is for preventing, ameliorating, or treating metabolic diseases, and contains an extract of Lysimachia mauritiana as an active ingredient. The extract of Lysimachia mauritiana not only reduces body weight, weight gain, food efficiency ratio, body fat, fat cell size, liver weight, liver fat accumulation, blood triglycerides, total cholesterol, and LDL cholesterol and improves GPT, but also has the effect of inhibiting adipocyte differentiation and fat accumulation in 3T3-L1 adipocytes, and thus can be effectively used as a health functional food or medicine for preventing, ameliorating, or treating metabolic diseases including obesity, dyslipidemia, and fatty liver. La présente invention concerne une composition qui est destinée à prévenir, améliorer ou traiter des maladies métaboliques, et contient un extrait de Lysimachia mauritiana en tant que principe actif. L'extrait de Lysimachia mauritiana non seulement réduit le poids corporel, le gain de poids, le ratio d'efficacité alimentaire, la graisse corporelle, la taille des cellules adipeuses, le poids du foie, l'accumulation de graisse hépatique, les triglycérides sanguins, le cholestérol total et le cholestérol LDL et améliore la GPT, mais a également pour effet d'inhiber la différenciation adipocytaire et l'accumulation de graisse dans les adipocytes 3T3-L1, et peut donc être efficacement utilisé en tant qu'aliment fonctionnel diététique ou médicament pour prévenir, améliorer ou traiter des maladies métaboliques comprenant l'obésité, la dyslipidémie et la stéatose hépatique. 본 발명은 갯까치수영 추출물을 유효성분으로 함유하는 대사성 질환의 예방, 개선 또는 치료용 조성물에 관한 것으로, 상기 갯까치수영 추출물이 체중 감소, 체중 증가량 감소, 식이효율 감소, 체지방 및 지방세포 크기 감소, 간 무게 및 간 지방 축적 감소, 혈중 중성지방 감소, 총 콜레스테롤 감소, LDL 콜레스테롤 감소, GPT 개선 뿐만 아니라, 3T3-L1 지방세포에서 지방세포 분화 및 지방축적 억제 효과가 있으므로, 비만, 이상지질혈증 또는 지방간을 포함하는 대사성 질환의 예방, 개선 또는 치료를 위한 건강기능식품 또는 의약품으로 유용하게 사용될 수 있다.