PYRAZOLO[1,5-A]PYRIDO[3,2-E]PYRIMIDINES AND PYRAZOLO[1,5-A][1,3]THIAZOLO[5,4-E]PYRIMIDINES AS P2X3 INHIBITORS FOR THE TREATMENT OF NEUROGENIC DISORDERS
The present invention relates to substituted pyrazolo[l,5-a]pyridine-[3,2-e]pyrimidines compounds of formula (I) wherein X, R1, and R2 are as defined in the claims, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the compounds for use i...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English French |
Published |
29.06.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to substituted pyrazolo[l,5-a]pyridine-[3,2-e]pyrimidines compounds of formula (I) wherein X, R1, and R2 are as defined in the claims, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the compounds for use in the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.
La présente invention concerne des composés pyrazolo[l,5-a]pyridine-[3,2-e]pyrimidines substitués de formule (I) dans laquelle X, R1 et R2 sont tels que définis dans les revendications, des procédés de préparation desdits composés, des compositions et combinaisons pharmaceutiques comprenant lesdits composés et les composés destinés à être utilisés dans le traitement ou la prophylaxie de maladies, en particulier de maladies neurogènes, en tant qu'agent unique ou en combinaison avec d'autres principes actifs. |
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Bibliography: | Application Number: WO2022EP86922 |