TREATMENT OF FGG RELATED DISEASES AND DISORDERS

Disclosed herein are compositions comprising an oligonucleotide that targets FGG. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating a mental disorder, or a condition associated with an FGG mutation. The...

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Bibliographic Details
Main Authors CAJES, Brian, VEKICH, John, BRUSE, Shannon, GOTTESMAN, Omri, ROZEMA, David, LEWIS, David
Format Patent
LanguageEnglish
French
Published 11.07.2024
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Summary:Disclosed herein are compositions comprising an oligonucleotide that targets FGG. The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating a mental disorder, or a condition associated with an FGG mutation. The method may include providing an oligonucleotide to a subject that targets FGG. L'invention concerne des compositions comprenant un oligonucléotide qui cible FGG. L'oligonucléotide peut comprendre un petit ARN interférent (ARNsi) ou un oligonucléotide antisens (ASO). L'invention concerne également des procédés de traitement d'un trouble mental, ou d'un état associé à une mutation de FGG. Le procédé peut comprendre la fourniture d'un oligonucléotide à un sujet qui cible FGG.
Bibliography:Application Number: WO2022US80933