ADENOSINE DEAMINASE 2 COMPOSITIONS AND METHODS FOR USING SAME

The invention is directed to mutants of adenosine deaminase 2 (ADA2) that have improved catalytic activity relative to wildtype ADA2, as well as compositions comprising the mutants and methods of using the mutants to treat various conditions. L'invention concerne des mutants d'adénosine dé...

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Bibliographic Details
Main Authors COX, John Robert, BLAZECK, John James
Format Patent
LanguageEnglish
French
Published 07.09.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention is directed to mutants of adenosine deaminase 2 (ADA2) that have improved catalytic activity relative to wildtype ADA2, as well as compositions comprising the mutants and methods of using the mutants to treat various conditions. L'invention concerne des mutants d'adénosine désaminase 2 (ADA2) qui présentent une activité catalytique améliorée par rapport à l'ADA2 de type sauvage, ainsi que des compositions comprenant les mutants et des méthodes d'utilisation des mutants pour traiter diverses affections.
Bibliography:Application Number: WO2022US79692