NUCLEIC ACID DETECTION KIT FOR DIAGNOSING LIVER CANCER

• Main Authors: WANG, Yupeng, JIANG, Ruijingfang, ZHOU, Jian, SUN, Jianlong, ZHU, Shida, GUO, Dezhen, YANG, Xinrong, LI, Zhilong, PENG, Jiaxi, HUANG, Ao, FAN, Jia, WANG, Yuying
• Format: Patent
• Language: Chinese; English; French
• Published: 19.05.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; TESTING; VINEGAR; WINE

Disclosed in the present invention is a nucleic acid detection kit for diagnosing liver cancer. Provided in the present invention is the use of a methylated OTX1 gene and a methylated HIST1H3G gene as markers in the diagnosis or screening of cancers, early warning of cancers before clinical symptoms, and distinguishing or assisted distinguishing of cancers from benign lesions. According to the present invention, the methylated OTX1 gene and the methylated HIST1H3G gene are used as markers for screening for liver cancer; and by means of detecting the methylation levels of OTX1 gene and HIST1H3G gene and analyzing the obtained data, the possibility of suffering from liver cancer in a subject can be predicted, thereby achieving the purpose of screening for liver cancer in the common population or population at high risk of liver cancer. La présente invention concerne un kit de détection d'acide nucléique pour diagnostiquer un cancer du foie. La présente invention concerne l'utilisation d'un gène OTX1 méthylé et