NOVEL LACTOBACILLUS PLANTARUM PROBIO 88, EXTRACT THEREOF, AND COMPOSITION

• Main Authors: HOR, Yan Yan, LEW, Lee Ching, PARK, Yong-Ha
• Format: Patent
• Language: English; French; Korean
• Published: 30.03.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FODDER; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention provides a Lactobacillus plantarum) Probio 88 strain and an extract and a composition, each containing same. The strain, extract, and composition according to the present invention have the effects of suppressing SARS-CoV-2 infection and replication, reducing the intracellular accumulation of inflammation and reactive oxygen species (ROS), decreasing extracellular signal-regulated kinase (ERK) activity, enhancing antiviral activity, and being able to be advantageously used as a therapeutic agent or adjuvant for coronaviral diseases. La présente invention concerne une souche Lactobacillus plantarum) Probio 88 ainsi qu'un extrait et une composition, chacun la contenant. La souche, l'extrait et la composition selon la présente invention présentent les effets de supprimer l'infection et la réplication du SARS-CoV-2, de réduire l'accumulation intracellulaire d'inflammation et d'espèces réactives de l'oxygène (ROS), de diminuer l'activité de la kinase régulée par le signal extracellulaire (ERK), de renforcer l'activité antivirale, et de pouvoir être avantageusement utilisés comme agent thérapeutique ou adjuvant contre les maladies coronavirales. 본 발명은 락토바실러스 플란타럼(Lactobacillus plantarum) Probio 88 균주와 이를 포함하는 추출물 및 조성물을 제공한다. 본 발명에 따른 균주, 추출물 및 조성물은 SARS-CoV-2 감염 및 복제를 억제하고, 염증 및 활성산소(ROS)의 세포내 축적량을 감소시키며, 세포외신호조절키나아제(ERK) 활성을 감소시키고, 항바이러스 활성을 향상시키며, 코로나바이러스 치료제 또는 보조치료제로 유용하게 사용될 수 있다는 발명의 효과를 가진다.