GLYCAN CONJUGATE COMPOSITIONS AND METHODS

The present disclosure provides methods and compositions for modulating cell surface proteins and receptor complexes using a novel class of glycan conjugates that can be used to engage the signaling pathways within desired c cell types. Such defined cell-targeting bioactive glycoligands are directed...

Full description

Saved in:
Bibliographic Details
Main Authors FLYNN, Ryan, GOODMAN, Brian, BISARIA, Namita, LAWLOR, Ciaran
Format Patent
LanguageEnglish
French
Published 16.03.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present disclosure provides methods and compositions for modulating cell surface proteins and receptor complexes using a novel class of glycan conjugates that can be used to engage the signaling pathways within desired c cell types. Such defined cell-targeting bioactive glycoligands are directed for cell engagement and activation in therapeutic applications. La présente divulgation concerne des méthodes et des compositions pour moduler des protéines de surface cellulaires et des complexes de récepteurs au moyen d'une nouvelle classe de conjugués de glycane qui peuvent être utilisés pour mobiliser les voies de signalisation dans des types de cellules c souhaités. De tels glycoligands bioactifs de ciblage de cellules définis sont dirigés pour une mobilisation et une activation de cellules dans des applications thérapeutiques.
Bibliography:Application Number: WO2022US76342