MICROSPHERE FACILITATED INTRACELLULAR DELIVERY AND ASSOCIATED METHODS AND DEVICES

Provided herein are methods and devices for microsphere facilitated intracellular delivery of exogenous cargo, comprising passing a solution comprising a plurality of cells and one or more exogeneous cargo through a matrix comprising a plurality of microspheres, wherein the one or more exogenous car...

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Bibliographic Details
Main Authors STOLOWITZ, Mark L, AKERS, Johnny C, THU, Mya S
Format Patent
LanguageEnglish
French
Published 09.03.2023
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Summary:Provided herein are methods and devices for microsphere facilitated intracellular delivery of exogenous cargo, comprising passing a solution comprising a plurality of cells and one or more exogeneous cargo through a matrix comprising a plurality of microspheres, wherein the one or more exogenous cargo is delivered to the plurality of cells. The methods further comprises incubating the solution for a period of time after passing the solution through the matrix. L'invention concerne des procédés et des dispositifs pour l'administration intracellulaire facilitée par des microsphères de charge exogène, comprenant le passage d'une solution comprenant une pluralité de cellules et une ou plusieurs charges exogènes à travers une matrice comprenant une pluralité de microsphères, la ou les charges exogènes étant administrées à la pluralité de cellules. Les procédés comprennent en outre l'incubation de la solution pendant une période de temps après le passage de la solution à travers la matrice.
Bibliography:Application Number: WO2022US75870