MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER

The present invention relates to compounds of formula (I), wherein R1 to R5 and A1 to A3 are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds. La présente invention concerne des composés de formule (I...

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Main Authors CHEN, Jianguo, SHEN, Hong, LIU, Haixia, YAO, Xiangyu, QIU, Hongxia, ZHU, Wei, YAN, Zhipeng, ZHAO, Dan, YANG, Beimeng, ZHANG, Weixing
Format Patent
LanguageEnglish
French
Published 02.03.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds of formula (I), wherein R1 to R5 and A1 to A3 are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds. La présente invention concerne des composés de formule (I), où R1 à R5 et A1 à A3 sont tels que décrits dans la description, et leurs sels pharmaceutiquement acceptables, et des compositions comprenant les composés et les procédés d'utilisation des composés.
Bibliography:Application Number: WO2022EP73542